Buy Mac Software and Help Cure Cancer
Seth Dillingham is running his 4th annual PMC Software Charity Fundraiser.
There are many Mac OS X and iPhone apps up for sale, you find apps you would like and make him an offer. All the proceeds go to charity.
Check it out and see if there is anything you can use. The Mac apps will usually have a trial version of some sort, so you can check them out before you buy.